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Generic Duphaston (Dydrogesterone)
Duphaston
Duphaston is a synthetic hormone applied in treatment of secondary amenorrhoea, dysfunctional uterine bleeding and post-menopausal symptoms.
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10mg
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Duphaston $58.00
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10mg
20pills
Duphaston $92.00
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10mg
30pills
Duphaston $118.00
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10mg
60pills
Duphaston $187.00
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10mg
90pills
Duphaston $253.00
$210.99
$2.34 per pill
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10mg
120pills
Duphaston $304.00
$252.99
$2.11 per pill
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save: $322.80
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Shiono Chemical Co. Mishell; Thomas H. No reports of ill effects from overdosage have been recorded. Only one previous systematic review has been performed [ 32 ]. It is estimated that during the period from to [71] around 38 million women were treated with dydrogesterone and that fetuses were exposed to dydrogesterone in utero in more than 10 million pregnancies. Kyorin Pharmacetical Co. The results of this metaanalysis of patients show that the effect of dydrogesterone on the risk of miscarriage in women with threatened miscarriage appears to be substantiated. The number of subsequent miscarriages or continuing pregnancies per randomized woman was compared in women receiving dydrogesterone compared to standard bed rest or placebo intervention. You should not use Duphaston tablets 10mg if you: are allergic to dydrogesterone or any other ingredient in Duphaston 10 are pregnant or planning to become pregnant, without discussion with your doctor have a past or family history of carcinoma of the breast, endometrial carcinoma or liver disease a history of thrombosis blood clots or stroke abnormal genital bleeding of unknown cause How should Duphaston be taken? Dydrogesterone is marketed mainly under the brand names Duphaston alone and Femoston in combination with estradiol. For patients who had achieved regular cycle at the end of treatment:. However, there are limited data regarding Duphaston's role in achieving cycle regularization from post-marketing settings. None of the studies, controlled for predictive factors for miscarriage, such as ultrasonic detection of a fetal heartbeat, fetal karyotyping, maternal age, body mass index, infertility, assisted conception, high alcohol consumption, low serum hCG levels, previous recurrent miscarriages and psychological stress [ 36—38 ]. I accept the Terms and Privacy Policy. Additionally, a literature search found no trials of the effect of oral progesterone on threatened miscarriage. Ketkar S. Alfresa Pharma corporation Amgen K. It is structurally and pharmacologically similar to natural progesterone has good oral bioavailability and few side effects. Please check and try again Please enter recipient's email Recipient's email is invalid. Early Hum Dev. Duphaston tablets Duphsaton are also used to treat endometriosis growth of endometrial tissue outside the uterus causing pain and bleedinginfertility and spontaneous abortion miscarriage ; and are to counteract the stimulating effect of oestrogen on the endometrium, therefore reducing the risk of endometrial cancer, which can develop in response to oestrogen in women taking hormone replacement therapy HRT for menopausal symptoms. Interactive image. Dydrogesterone is synthesized and manufactured by treatment of progesterone with ultraviolet light exposure. Department of Health and Human Services. National Center for Biotechnology InformationU. SKI Pharma Co. Stat, at once; b. Duphaston 10 counteracts the stimulating effect of oestrogen on the endometrium, reducing the risk of endometrial cancer, which can develop in response to an oestrogen, in women taking HRT for menopausal symptoms. Fertil Steril. Schindler AE February Acta Obstet Gynecol Scand Suppl. Side Effects. Kalinka and Szekeres-Bartho [ 19 ]; Kalinka and Radwan [ 20 ]. Duphaston tablets 10mg contain dydrogesterone, a synthetic progesterone, used to treat a variety of conditions resulting from a lack of endogenous naturally produced progesterone, including menstrual disorders and endometriosis, and for hormone replacement therapy HRT and transgender hormone therapy. None of the studies, controlled for predictive factors for miscarriage, such as ultrasonic detection of a fetal heartbeat, fetal karyotyping, maternal age, body mass index, infertility, assisted conception, high alcohol consumption, low serum hCG levels, previous recurrent miscarriages and psychological stress [ 36—38 ]. Inclusion Criteria Women aged 18 years or older Suffering from irregular menstrual cycle for at least 3 months and for whom the physician decides to prescribe Duphaston, in accordance with locally approved package insert Patients willing to sign written authorization to provide data for the study Exclusion Criteria Patients having known hypersensitivity to the active ingredient or excipients Patients having known or suspected progesterone-dependent neoplasms Patients having vaginal bleeding of unknown etiology Patients taking oral contraceptives Pregnant and lactating patients Any other condition that precludes use of Duphaston in a particular patient, in accordance with the contraindication, precautions and special warnings listed in the locally approve package insert for example, patients with history of liver disease, porphyria or depression Patients not willing to sign written authorization for data release consent form. Read More: Cremaffin Cyclopam Pantocid. Treating endometriosis with Duphaston Duphaston tablets 10mg Duphasotn dydrogesterone, a synthetic derivative of the female sex hormone progesterone, which means that Diphaston chemical structure closely resembles that of naturally produced progesterone and it therefore works in a similar way. No genital abnormalities, no effect on hemato-poietic system, liver or kidney function. Kyowa Kirin Co. It is used for treating medical ailments caused due to the lack of hormones. Twenty-one reports of dydrogesterone treatment were identified with patients. Bashmakova et al. This steroidal progestin works by reducing the growth of the endometrium in the body. Study Description. Do you wish to continue and exit this website? Read our disclaimer for details. Maternal serum inhibin A levels may predict pregnancy outcome in women with threatened Duphaston. Torii Pharmaceutical Co. Ans: Yes, the use of this drug may cause irregular menstruation. Sonography of pregnancies with first-trimester bleeding and a viable embryo: a study of prognostic indicators by logistic regression analysis. Thus, it is suggested to refrain from consuming alcohol while administering Duphaston. It acts on the Dupbaston lining of the uterus Duphastoh the proliferating phase to the secretory phase. Treating menstrual problems with Duphaston Duphaston tablets 10mg contain dydrogesterone, a synthetic derivative of the female sex hormone progesterone, which means that its chemical structure closely resembles that of naturally produced progesterone and it therefore works in a similar way. Kowa Co. Duphaston tablets 10mg contain dydrogesterone, a synthetic progesterone, used to treat a variety of conditions resulting from a lack of endogenous naturally produced progesterone, including menstrual disorders and endometriosis, and for hormone replacement therapy HRT and transgender hormone therapy. Luteectomy evidence. Ans: Duphaston tablet is not recommended to be taken by patients suffering from the following conditions: Brain cancer Breast cancer Liver dysfunction Patients who are not at any risk of abortion Stroke Breastfeeding Mothers Hypersensitivity Advanced pregnancy Blood clots disorder Undiagnosed abnormal vaginal bleeding 13 What are the appropriate storage requirements for Duphaston tablet? Nippon-Chemiphar CO. Other medicines that contain: dydrogesterone. Curr Opin Obstet Gynecol.
Common use

Duphaston contains dydrogesterone, a synthetic hormone similar to progesterone. The medication is used to restore the hormone balance when synthesis of progesterone in the body is not sufficient (sterility, abortion, premenstrual syndrome, dysmenorrhea, irregular menstruation, secondary amenorrhea, dysfunctional uterine bleeding). The medication stimulates beginning of the secretory phase in the endometrium thereby reducing the risk of endometrial hyperplasia and carcinogenesis, which increases due to estrogen.



Dosage and direction

Each condition requires special treatment and dose schedule. Follow all instructions of your doctor. To treat endometriosis take 10 mg of Duphaston two or three times a day from 5th to 25th day of your cycle. To treat infertility take 10 mg a day from 14th to 25th day of your cycle. The treatment should be done continuously for three, six and more following cycles. Contact your doctor about all details.



Precautions

Inform your doctor if you are pregnant or breastfeeding before to take this medication. Hormone replacement therapy should not be administered without a general medical examination, including pelvic examination. Your doctor may ask you to make mammogram examination regularly.



Contraindications

This medication cannot be used in individuals with hypersensitivity to Duphaston, Dubin-Johnson syndrome (an increase of conjugated bilirubin without elevation of liver enzymes), Rotor syndrome (a benign autosomal recessive bilirubin disorder).



Side effects

The most frequent adverse reactions include headache, nausea, dizziness, bloating, skin reactions (rash and itching), breast tenderness, menstrual spotting between periods



Drug interaction

Inductors of microsomal liver enzymes such as phenobarbital may accelerate the metabolism of Duphaston and weaken its effect.



Missed dose

If you forgot to take a dose contact your doctor about necessary actions.



Overdose

There is not information about possible overdose. Seek immediate medical help if you suspect overdose.



Storage

Store at room temperature between 20-25 C (68-77 F). Store away from moisture, heat, and sunlight. It is not recommended to store in a bathroom and places available for children.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
Testimonials
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